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Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020) (universityofcalifornia.edu)

633 points by whalesalad · 1664 days ago · 449 comments on HN

Article summary

A study by UC Riverside researchers found that soybean oil, the most widely consumed cooking oil in the US, causes genetic changes in the brain of mice, potentially leading to neurological conditions such as autism, Alzheimer's disease, and depression. The study compared mice fed diets high in fat from soybean oil, modified soybean oil, and coconut oil. The researchers found that soybean oil affected the hypothalamus, a part of the brain that regulates body weight, metabolism, and stress response. The study's findings suggest that soybean oil may not be as healthy as previously thought.

Main themes

  • soybean oil health effects
  • genetic changes vs gene expression
  • diet and lifestyle
  • saturated fats and cardiovascular disease
  • cultural and individual tolerance to different oils
  • nutrition and public health
  • research methodology and applicability

What commenters say

  • Soybean oil's effects on gene expression, rather than genetic changes, are the actual findings of the study.
  • The study's results may not be directly applicable to humans, as it was conducted on mice.
  • Ghee, a type of clarified butter, is not necessarily unhealthy and has been consumed in India for thousands of years.
  • The adoption of Western diets and lifestyles may be a contributing factor to the increasing rates of diabetes and obesity in India.
  • Saturated fats, including those found in coconut oil and ghee, may have negative health effects, particularly in relation to cardiovascular disease.
  • The health effects of different oils and fats depend on various factors, including individual tolerance, lifestyle, and overall diet.
  • Reducing consumption of soybean oil and other seed oils may be beneficial for overall health.
  • More research is needed to fully understand the effects of different oils and fats on human health.