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U.S. surgeons transplant pig heart into human patient (apnews.com)

804 points by danso · 1712 days ago · 701 comments on HN

Article summary

A US patient received a pig heart transplant after being deemed ineligible for a human heart transplant and an artificial heart pump due to uncontrollable arrhythmia. The pig heart was genetically edited to remove a sugar responsible for hyper-fast organ rejection. The patient had no other options and was dying. The procedure's success and the patient's prognosis are unknown.

Main themes

  • xenotransplantation
  • artificial hearts
  • organ compatibility
  • genetic engineering
  • medical ethics
  • transplantation risks and benefits

What commenters say

  • The use of a pig heart in the transplant raises questions about the compatibility and availability of pig hearts compared to other animals, such as primates.
  • Artificial hearts are not yet a viable option for some patients due to limitations and risks, including arrhythmia and high rates of infection and stroke.
  • The development of artificial hearts and xenotransplantation are crucial for addressing the shortage of human organs available for transplant.
  • Some people believe that a pig heart might be a better option than an artificial one, while others think that artificial hearts will eventually become the preferred choice.
  • The genetic engineering of pigs to make their organs more compatible with humans is a necessary step for xenotransplantation to be successful.
  • The long-term survival and quality of life of patients with artificial hearts or xenotransplanted organs are significant concerns.
  • The use of pig hearts in transplants may be more feasible due to fewer ethical concerns compared to using primates.
  • The success of this transplant could be a step towards the development of more advanced and reliable artificial hearts or xenotransplanted organs.